Cardiothoracic Surgery

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Thoracic Clinical Trials

  1. A Phase III Randomized Trial of Lobectomy versus Sublobar Resection for Small (< 2cm) Peripheral Non-Small Cell Lung Cancer (CALGB 140503).

    This randomized trial is studying different types of surgery to compare how well they work in treating patients with stage IA non-small cell lung cancer.

    Sublobar resection (wedge resection or segmentectomy) may be less invasive types of surgery than lobectomy for non-small cell lung cancer and may have fewer side effects and improve recovery. It is not yet known whether wedge resection or segmentectomy are more effective than lobectomy in treating stage IA non-small cell lung cancer.

    Patients will be randomized to receive a Lobectomy or a Sublobar Resection. After completion of study treatment, patients are followed up every 6 months for 2 years and then annually for 5 years.


    • Men and women age 18 and older
    • Suspected or proven non-small cell lung cancer
    • Peripheral lung nodule = 2 cm on preoperative CT scan and presumed to be lung cancer
    • No prior malignancy within 5 years other than non-melanoma skin cancer, superficial bladder cancer, or CIS of the cervix
    • The tumor location must be suitable for either lobar or sublobar resection (wedge or segment)

    Additional eligibility to be discussed when you contact the study team.

    PRIMARY INVESTIGATOR: Altorki, Nasser M.D.
    STATUS: Open to Enrollment
    DISEASE: Non-small Cell Lung Cancer
    CONTACT: Cathy Spinelli, R.N. (212) 746-3328
    PROTOCOL ID: WCMC IRB #0709009395
    Cancer and Leukemia Group B
    National Cancer Institute
    STUDY TYPE: Interventional
    PHASE: 3

  2. The EMPrint™ Ablate and RESect Study in Patients with Metastatic Lung Tumors (EMPRESS)

Contact Information

Cathy Spinelli, R.N.
Clinical Research Nurse
(212) 746-3328

Weill Cornell Medicine Cardiothoracic Surgery 525 East 68th Street
Box 110
Suite M 404
New York, NY 10065 Directions
Phone: (212) 746-5166